🕓 Last Updated on: July 24, 2026

Dosage Calculations NCLEX Dosage Calculations Practice Test #4: Heparin, Insulin & Units

Heparin and insulin calculations trip up many nursing students because these medications are dosed in units, not milligrams, and errors can be dangerous.

This free timed quiz includes 10 heparin and insulin dosage practice questions with answers and rationales, covering units/mL concentrations, pump rates in mL/hr, weight-based heparin boluses, and combining insulin doses.

The key move: find the concentration (units ÷ mL), then divide the ordered units/hr by that concentration to get the pump rate.

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All 10 Questions With Answers & Rationales

Prefer to work at your own pace? Every question from the timed quiz above is listed here in full. Solve each on paper, then tap Show Answer & Rationale to check your work.

Question 1: Heparin

A heparin infusion is ordered at 1,000 units/hr. The bag contains 25,000 units in 500 mL of D5W. At what rate in mL/hr should the nurse set the pump?

  • A. 25 mL/hr
  • B. 20 mL/hr
  • C. 50 mL/hr
  • D. 10 mL/hr
Show Answer & Rationale

Answer: B. 20 mL/hr

Rationale: Concentration = 25,000 units ÷ 500 mL = 50 units/mL. Rate = 1,000 units/hr ÷ 50 units/mL = 20 mL/hr.

Question 2: Heparin

A heparin bag has 20,000 units in 500 mL. The pump is running at 30 mL/hr. How many units/hr is the client receiving?

  • A. 600 units/hr
  • B. 1,200 units/hr
  • C. 1,500 units/hr
  • D. 900 units/hr
Show Answer & Rationale

Answer: B. 1,200 units/hr

Rationale: Concentration = 20,000 units ÷ 500 mL = 40 units/mL. Units/hr = 40 units/mL × 30 mL/hr = 1,200 units/hr.

Question 3: Insulin

A vial of insulin is labeled 100 units/mL. The order is for 35 units. How many mL should the nurse draw up in an insulin syringe?

  • A. 3.5 mL
  • B. 0.035 mL
  • C. 0.35 mL
  • D. 35 mL
Show Answer & Rationale

Answer: C. 0.35 mL

Rationale: (35 units ÷ 100 units) × 1 mL = 0.35 mL. (In practice, insulin is measured directly on a unit-marked insulin syringe.)

Question 4: Heparin

A provider orders a heparin bolus of 80 units/kg for a client weighing 70 kg. How many units should the nurse administer?

  • A. 560 units
  • B. 8,000 units
  • C. 5,600 units
  • D. 1,600 units
Show Answer & Rationale

Answer: C. 5,600 units

Rationale: Bolus = 80 units/kg × 70 kg = 5,600 units.

Question 5: Units/min

A heparin drip is set to deliver 18 units/kg/hr for a 90 kg client. How many units/hr will the client receive?

  • A. 162 units/hr
  • B. 1,620 units/hr
  • C. 1,800 units/hr
  • D. 900 units/hr
Show Answer & Rationale

Answer: B. 1,620 units/hr

Rationale: Units/hr = 18 units/kg/hr × 90 kg = 1,620 units/hr.

Question 6: Insulin

An order reads: regular insulin 12 units and NPH insulin 28 units subcutaneously. What is the total number of units the nurse draws into one syringe?

  • A. 16 units
  • B. 24 units
  • C. 40 units
  • D. 30 units
Show Answer & Rationale

Answer: C. 40 units

Rationale: Total = 12 units + 28 units = 40 units. Draw up the regular (clear) insulin first, then NPH (cloudy).

Question 7: Heparin

A heparin infusion contains 25,000 units in 250 mL. The order is 800 units/hr. What is the correct pump rate in mL/hr?

  • A. 16 mL/hr
  • B. 8 mL/hr
  • C. 10 mL/hr
  • D. 4 mL/hr
Show Answer & Rationale

Answer: B. 8 mL/hr

Rationale: Concentration = 25,000 units ÷ 250 mL = 100 units/mL. Rate = 800 units/hr ÷ 100 units/mL = 8 mL/hr.

Question 8: Insulin Drip

An insulin drip has 100 units in 100 mL of normal saline. The order is 6 units/hr. At what rate in mL/hr should the pump be set?

  • A. 3 mL/hr
  • B. 12 mL/hr
  • C. 6 mL/hr
  • D. 10 mL/hr
Show Answer & Rationale

Answer: C. 6 mL/hr

Rationale: Concentration = 100 units ÷ 100 mL = 1 unit/mL. Rate = 6 units/hr ÷ 1 unit/mL = 6 mL/hr.

Question 9: Heparin

A client on a heparin drip weighs 80 kg. The protocol calls for a rate increase of 2 units/kg/hr. By how many units/hr should the infusion be increased?

  • A. 16 units/hr
  • B. 80 units/hr
  • C. 160 units/hr
  • D. 200 units/hr
Show Answer & Rationale

Answer: C. 160 units/hr

Rationale: Increase = 2 units/kg/hr × 80 kg = 160 units/hr.

Question 10: Insulin

An insulin vial contains 100 units/mL. The order is 22 units. Using a tuberculin syringe (mL), how many mL equals this dose?

  • A. 2.2 mL
  • B. 0.022 mL
  • C. 0.44 mL
  • D. 0.22 mL
Show Answer & Rationale

Answer: D. 0.22 mL

Rationale: (22 units ÷ 100 units) × 1 mL = 0.22 mL. An insulin syringe is preferred, but this shows the mL equivalent.

Free NCLEX Prep

NCLEX Dosage Calculation Practice Tests

Master the medication math that shows up most on the NCLEX with 75 free, timed dosage questions — complete with answers and step-by-step rationales. Work through all six tests to build speed and confidence.

6
Timed Tests
75
Questions
100%
Free
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Anna Curran. RN, BSN, PHN

Anna Curran, RN, BSN, PHN is a Critical Care ER nurse with over 30 years of bedside experience. She has taught BSN and LVN students and began writing study guides to strengthen their knowledge, especially for NCLEX success. Anna founded Nursestudy.net to share evidence‑based nursing diagnoses, care plans, and clinical review materials that support safe, up‑to‑date nursing practice.