🕓 Last Updated on: October 18, 2026

Lab Values & ABGs Practice Test #4: ABG Basics

This free Lab Values & ABGs Practice Test #4 covers ABG basics: normal values for pH, PaCO2, bicarbonate and PaO2, a step-by-step way to read a blood gas, respiratory and metabolic acidosis and alkalosis, oxygenation, and safe ABG sampling. Work through 10 timed questions, then check every answer with the full rationales below. No sign-up required.

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All 10 Questions With Answers & Rationales

Prefer to work at your own pace? Every question from the timed quiz above is listed here in full. Choose your answer, then tap Show Answer & Rationale to check it.

Question 1: Normal ABG Values

The nurse is reviewing arterial blood gas (ABG) results for four adult clients breathing room air. Which set of results falls within typical adult reference ranges?

  • A. pH 7.32, PaCO2 40 mm Hg, HCO3 20 mEq/L, PaO2 90 mm Hg
  • B. pH 7.48, PaCO2 30 mm Hg, HCO3 24 mEq/L, PaO2 95 mm Hg
  • C. pH 7.40, PaCO2 40 mm Hg, HCO3 24 mEq/L, PaO2 92 mm Hg
  • D. pH 7.38, PaCO2 52 mm Hg, HCO3 30 mEq/L, PaO2 70 mm Hg
Show Answer & Rationale

Answer: C. pH 7.40, PaCO2 40 mm Hg, HCO3 24 mEq/L, PaO2 92 mm Hg

Rationale: Typical adult arterial ranges are pH 7.35 to 7.45, PaCO2 35 to 45 mm Hg, HCO3 (bicarbonate) 22 to 26 mEq/L, and PaO2 about 80 to 100 mm Hg on room air. Ranges vary slightly by lab, and PaO2 is often lower in older adults, so always check your facility's reference values. Option C is normal on every value. Option A has a low pH and low bicarbonate (metabolic acidosis). Option B has a high pH and low PaCO2 (respiratory alkalosis). Option D has a pH inside the normal range, but the PaCO2 and bicarbonate are both high and the PaO2 is low, so it is not a normal gas. That pattern shows the body making up for a long-standing problem (compensation), which is covered in Test #5.

Question 2: Reading an ABG Step by Step

A nursing student asks how to begin interpreting an arterial blood gas. Which step should the nurse tell the student to do first?

  • A. Look at the bicarbonate to decide whether the kidneys are working.
  • B. Look at the PaO2 to decide whether the client needs oxygen.
  • C. Compare the PaCO2 with the bicarbonate to see which one is more abnormal.
  • D. Look at the pH to decide whether the blood is acidotic, alkalotic or within the normal range.
Show Answer & Rationale

Answer: D. Look at the pH to decide whether the blood is acidotic, alkalotic or within the normal range.

Rationale: Start with the pH: below 7.35 is acidosis, above 7.45 is alkalosis. Next, look at the PaCO2 (the respiratory value) and the bicarbonate (the metabolic value) and decide which one explains the pH. A memory aid is ROME: Respiratory Opposite, Metabolic Equal. In a respiratory problem the pH and PaCO2 move in opposite directions (pH down, PaCO2 up). In a metabolic problem the pH and bicarbonate move in the same direction (pH down, HCO3 down). Only after that do you check whether the other system is compensating. The PaO2 tells you about oxygenation, not acid-base balance; it matters, but it is read separately and does not tell you whether the client is acidotic. Always read the numbers alongside the client's assessment, never on their own.

Question 3: Respiratory Acidosis

A client received several doses of an IV opioid for pain after surgery. The client is difficult to rouse, with a respiratory rate of 8/min and shallow breathing. ABG results: pH 7.28, PaCO2 59 mm Hg, HCO3 25 mEq/L. How should the nurse interpret these results?

  • A. Uncompensated respiratory acidosis caused by hypoventilation
  • B. Uncompensated metabolic acidosis caused by loss of bicarbonate
  • C. Respiratory alkalosis caused by rapid breathing
  • D. Compensated metabolic alkalosis caused by the opioid
Show Answer & Rationale

Answer: A. Uncompensated respiratory acidosis caused by hypoventilation

Rationale: The pH is low (acidosis) and the PaCO2 is high, so the problem is respiratory: pH and PaCO2 have moved in opposite directions. The bicarbonate is normal, so the kidneys have not yet compensated, which fits a sudden problem. Slow, shallow breathing from opioid sedation lets carbon dioxide build up, and CO2 acts as an acid in the blood. The nurse treats the cause: try to rouse the client and coach deep breaths, stop further opioid doses, give oxygen and naloxone according to orders or the facility's protocol, monitor respiratory rate, sedation level and oxygen saturation closely, and notify the provider or rapid response team. Remember that a normal oxygen saturation on supplemental oxygen can hide rising CO2.

Question 4: Respiratory Alkalosis

A client who is very anxious is breathing 32 times per minute and reports lightheadedness and tingling in the fingers and around the mouth. ABG results: pH 7.50, PaCO2 29 mm Hg, HCO3 23 mEq/L. Which statement best explains these findings?

  • A. The client has metabolic alkalosis from too much bicarbonate, which is causing the tingling.
  • B. The client has respiratory acidosis because rapid breathing traps carbon dioxide.
  • C. The results are normal for a client who is anxious, so no further assessment is needed.
  • D. The client has respiratory alkalosis from blowing off carbon dioxide, and alkalosis lowers ionized calcium, which causes the tingling.
Show Answer & Rationale

Answer: D. The client has respiratory alkalosis from blowing off carbon dioxide, and alkalosis lowers ionized calcium, which causes the tingling.

Rationale: The pH is high (alkalosis) and the PaCO2 is low, moving in opposite directions, so this is respiratory alkalosis. The bicarbonate is normal, so there is no compensation yet. Breathing fast and deep removes carbon dioxide faster than the body makes it. Alkalosis makes more calcium bind to albumin, so less ionized (active) calcium is available, which causes numbness and tingling around the mouth and in the fingers, and sometimes muscle cramps. The nurse should not assume anxiety is the cause: pain, hypoxemia, fever, sepsis and pulmonary embolism can also cause rapid breathing and must be ruled out. Once physical causes are addressed, the nurse stays with the client and coaches slow breathing. Breathing into a paper bag is no longer recommended because it can lower oxygen levels.

Question 5: Metabolic Alkalosis

A client has had a nasogastric tube to low continuous suction for 3 days after bowel surgery. ABG results: pH 7.51, PaCO2 44 mm Hg, HCO3 33 mEq/L. Which interpretation is correct?

  • A. Respiratory alkalosis from pain and rapid breathing
  • B. Metabolic alkalosis from loss of hydrochloric acid in the gastric drainage
  • C. Metabolic acidosis from loss of bicarbonate in the gastric drainage
  • D. Respiratory acidosis from shallow breathing after abdominal surgery
Show Answer & Rationale

Answer: B. Metabolic alkalosis from loss of hydrochloric acid in the gastric drainage

Rationale: The pH is high and the bicarbonate is high, moving in the same direction, so the problem is metabolic alkalosis. The PaCO2 is still within the normal range, so the lungs have not compensated in a meaningful way. Gastric fluid is rich in hydrochloric acid, so ongoing NG suction or vomiting removes acid and leaves excess bicarbonate. These clients often lose potassium and chloride as well, and low potassium makes the alkalosis harder to correct. The nurse monitors potassium and other electrolytes, measures NG output accurately, watches for weakness, dysrhythmias and confusion, and gives the fluid and electrolyte replacement that is prescribed. Lower GI losses such as diarrhea do the opposite: they remove bicarbonate and cause acidosis.

Question 6: Metabolic Acidosis

A client has had severe watery diarrhea for 4 days. ABG results: pH 7.31, PaCO2 37 mm Hg, HCO3 18 mEq/L. How should the nurse interpret these results?

  • A. Metabolic acidosis caused by loss of bicarbonate in the stool
  • B. Metabolic alkalosis caused by loss of acid in the stool
  • C. Respiratory acidosis caused by weak breathing from dehydration
  • D. Normal results, because only the pH is outside its range
Show Answer & Rationale

Answer: A. Metabolic acidosis caused by loss of bicarbonate in the stool

Rationale: The pH is low and the bicarbonate is low, moving in the same direction, so this is metabolic acidosis. The PaCO2 is still normal, so the lungs have not yet compensated by breathing off more CO2. Intestinal fluid below the stomach is rich in bicarbonate, so heavy diarrhea removes base and leaves the blood more acidic. Other common causes of metabolic acidosis include diabetic ketoacidosis, lactic acidosis from shock or sepsis, and kidney failure. Option D is wrong because the bicarbonate is also low. The nurse watches for deep, rapid breathing, confusion and dysrhythmias, monitors potassium (diarrhea also removes potassium), tracks intake and output and weight, and gives the fluids and electrolytes that are prescribed.

Question 7: After an Arterial Puncture

A respiratory therapist has just drawn an ABG from the radial artery of a client who is receiving a continuous heparin infusion. Which action is most appropriate for the site?

  • A. Apply light pressure for 30 seconds and cover the site with an adhesive bandage.
  • B. Hold firm, direct pressure on the site for at least 5 minutes, and longer because the client is on heparin, then check the site and the pulse and circulation below it.
  • C. Have the client open and close the hand several times to restore blood flow to the wrist.
  • D. Place a warm compress over the site to help the artery close.
Show Answer & Rationale

Answer: B. Hold firm, direct pressure on the site for at least 5 minutes, and longer because the client is on heparin, then check the site and the pulse and circulation below it.

Rationale: Arteries are under high pressure, so an arterial puncture needs firm, direct pressure until bleeding has fully stopped. Many protocols call for at least 5 minutes, and longer, often 10 minutes or more, for clients on anticoagulants or with bleeding problems. Follow your facility's policy and keep holding until no bleeding or swelling is seen. Afterward the nurse checks the site for bleeding or a hematoma and checks color, warmth, sensation and the pulse below the site. Thirty seconds of light pressure is not enough and risks a hematoma. Moving the wrist and applying warmth encourage bleeding. Before a radial puncture, many facilities also require a check of collateral blood flow to the hand, such as the modified Allen test.

Question 8: Oxygenation and PaO2

A client with pneumonia is breathing room air and has an oxygen saturation of 89%. ABG results: pH 7.42, PaCO2 38 mm Hg, HCO3 24 mEq/L, PaO2 58 mm Hg. Which interpretation and action by the nurse is best?

  • A. The client has respiratory acidosis; encourage coughing and recheck the ABG tomorrow.
  • B. All of the results are within normal limits, so no action is needed.
  • C. The acid-base values are within normal range, but the client is hypoxemic; apply oxygen as prescribed or per protocol and notify the provider.
  • D. The client has metabolic alkalosis and needs fluids to correct it.
Show Answer & Rationale

Answer: C. The acid-base values are within normal range, but the client is hypoxemic; apply oxygen as prescribed or per protocol and notify the provider.

Rationale: Acid-base balance and oxygenation are two separate questions. Here the pH, PaCO2 and bicarbonate are all within typical ranges, so there is no acid-base imbalance. The PaO2, though, is well below the usual 80 to 100 mm Hg on room air, and together with an SpO2 of 89% it shows hypoxemia. The nurse starts oxygen according to the order or the facility's protocol, raises the head of the bed, assesses work of breathing and mental status, and reports the findings. Oxygen saturation targets differ between clients, for example in some clients with chronic lung disease, so follow the prescribed target. Option B misses the low PaO2. Options A and D describe acid-base problems that are not present.

Question 9: Asthma and a Rising PaCO2

A client is having a severe asthma attack. An ABG one hour ago showed pH 7.48 and PaCO2 31 mm Hg. Now the client is more drowsy, the wheezing is quieter, SpO2 is 88% on oxygen, and a repeat ABG shows pH 7.34 and PaCO2 49 mm Hg. What should the nurse conclude?

  • A. The client is improving, because the pH is moving back toward normal.
  • B. The quieter wheezing shows that the bronchospasm is resolving.
  • C. The values are close to normal, so the nurse should continue the current plan and recheck in 4 hours.
  • D. The client is tiring and moving toward respiratory failure; the nurse should call the rapid response team or provider immediately and stay with the client.
Show Answer & Rationale

Answer: D. The client is tiring and moving toward respiratory failure; the nurse should call the rapid response team or provider immediately and stay with the client.

Rationale: Early in an asthma attack, clients breathe fast and the PaCO2 falls, causing respiratory alkalosis, as the first result shows. When the PaCO2 climbs back to normal or above during a severe attack, it means the client can no longer move enough air, usually from fatigue and severe airway narrowing. The new result is now respiratory acidosis (pH below 7.35, PaCO2 above 45). Quieter wheezing with more drowsiness and falling saturation is an ominous sign, sometimes called a silent chest, because too little air is moving to make a wheeze. The nurse calls for help at once, stays with the client, keeps the head of the bed up, gives the treatments that are ordered, and prepares for possible ventilatory support.

Question 10: Sending an ABG Sample

The nurse is sending an ABG sample to the lab for a client who is receiving oxygen through a nasal cannula. Which information is most important to include with the specimen?

  • A. The oxygen delivery device and flow rate (or FiO2), and the client's temperature
  • B. The client's oxygen saturation from the day before
  • C. The time of the client's last meal
  • D. The name of the client's admitting diagnosis only
Show Answer & Rationale

Answer: A. The oxygen delivery device and flow rate (or FiO2), and the client's temperature

Rationale: The PaO2 can only be judged correctly if the lab and provider know how much oxygen the client was receiving when the sample was drawn, so record the device and flow rate or FiO2 (and ventilator settings if used). Many labs also ask for the client's temperature, because temperature affects blood gas values, along with the time the sample was drawn. If oxygen settings were just changed or the client was just suctioned, many facilities wait a set time, often 20 to 30 minutes, before drawing the sample; follow your policy. The sample is labeled, any air bubbles are removed, the syringe is capped, and it is sent right away. If there will be a delay, follow the lab's instructions, which often call for placing it on ice. Yesterday's saturation and meal time do not help interpret this sample.

Next: Test #5 — ABG Compensation →
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Anna Curran. RN, BSN, PHN

Anna Curran, RN, BSN, PHN is a Critical Care ER nurse with over 30 years of bedside experience. She has taught BSN and LVN students and began writing study guides to strengthen their knowledge, especially for NCLEX success. Anna founded Nursestudy.net to share evidence‑based nursing diagnoses, care plans, and clinical review materials that support safe, up‑to‑date nursing practice.