Nephrotic Syndrome Nursing Diagnosis & Care Plan

Nephrotic syndrome is a kidney disorder characterized by heavy proteinuria, hypoalbuminemia, edema, and hyperlipidemia. This nursing diagnosis focuses on identifying and managing symptoms, preventing complications, and improving patient outcomes through comprehensive care planning.

Causes (Related to)

Nephrotic syndrome can develop due to various underlying conditions and factors affecting kidney function:

  • Primary kidney diseases:
    • Minimal change disease
    • Focal segmental glomerulosclerosis
    • Membranous nephropathy
  • Secondary causes:
  • Risk factors include:
    • Genetic predisposition
    • Autoimmune disorders
    • Certain medications
    • Infections
    • Cancer

Signs and Symptoms (As evidenced by)

Nephrotic syndrome presents with characteristic signs and symptoms that nurses must recognize for accurate diagnosis and treatment.

Subjective: (Patient reports)

  • Fatigue and weakness
  • Decreased appetite
  • Foamy urine
  • Shortness of breath
  • Abdominal pain
  • Joint pain
  • Difficulty with movement due to edema

Objective: (Nurse assesses)

  • Generalized edema
  • Weight gain
  • Decreased urine output
  • Elevated blood pressure
  • Pallor
  • Ascites
  • Laboratory findings:
  • Proteinuria >3.5g/24hrs
  • Hypoalbuminemia <3.5g/dL
  • Elevated cholesterol
  • Elevated triglycerides

Expected Outcomes

The following outcomes indicate successful management of nephrotic syndrome:

  • The patient will demonstrate reduced edema
  • The patient will maintain optimal fluid balance
  • The patient will show improved nutritional status
  • The patient will maintain normal blood pressure
  • The patient will demonstrate an understanding of disease management
  • The patient will avoid complications
  • The patient will adhere to the prescribed medication regimen

Nursing Assessment

Monitor Vital Signs

  • Check blood pressure every 4 hours
  • Monitor heart rate and respiratory rate
  • Track daily weight
  • Assess temperature

Evaluate Fluid Status

  • Monitor intake and output strictly
  • Assess edema location and degree
  • Check for ascites
  • Evaluate skin turgor
  • Monitor for signs of fluid overload

Assess Nutritional Status

  • Monitor protein intake
  • Track caloric intake
  • Assess appetite
  • Monitor weight changes
  • Check albumin levels

Monitor for Complications

  • Assess for thrombosis signs
  • Watch for infection indicators
  • Monitor for respiratory distress
  • Check for signs of malnutrition
  • Evaluate for renal failure symptoms

Review Medication Compliance

  • Assess understanding of medications
  • Monitor response to treatment
  • Check for side effects
  • Verify proper administration
  • Document adherence

Nursing Care Plans

Nursing Care Plan 1: Excess Fluid Volume

Nursing Diagnosis Statement:
Excess Fluid Volume related to decreased plasma oncotic pressure secondary to hypoalbuminemia as evidenced by peripheral edema, weight gain, and decreased urine output.

Related Factors:

  • Decreased plasma protein levels
  • Sodium and water retention
  • Impaired kidney function
  • Altered membrane permeability

Nursing Interventions and Rationales:

  1. Monitor daily weights at the same time and conditions
    Rationale: Indicates fluid status changes and treatment effectiveness
  2. Assess edema location and degree
    Rationale: Tracks progression of fluid retention
  3. Maintain strict I&O records
    Rationale: Helps evaluate fluid balance and treatment effectiveness
  4. Administer diuretics as prescribed
    Rationale: Promotes fluid elimination and edema reduction

Desired Outcomes:

  • The patient will demonstrate decreased edema
  • The patient will maintain a stable weight
  • The patient will show improved urine output
  • The patient will maintain an effective breathing pattern

Nursing Care Plan 2: Risk for Infection

Nursing Diagnosis Statement:
Risk for Infection related to decreased immune function and protein loss as evidenced by low albumin levels and immunosuppressive therapy.

Related Factors:

  • Compromised immune system
  • Protein loss in urine
  • Use of immunosuppressive medications
  • Presence of edema

Nursing Interventions and Rationales:

  1. Monitor for signs of infection
    Rationale: Enables early detection and treatment
  2. Maintain aseptic technique
    Rationale: Prevents introduction of pathogens
  3. Educate about infection prevention
    Rationale: Empowers patient to prevent infections

Desired Outcomes:

  • The patient will remain free from infection
  • The patient will demonstrate proper hygiene techniques
  • The patient will identify early signs of infection

Nursing Care Plan 3: Imbalanced Nutrition

Nursing Diagnosis Statement:
Imbalanced Nutrition: Less than Body Requirements related to protein loss and decreased appetite as evidenced by hypoalbuminemia and unintentional weight loss.

Related Factors:

  • Protein loss through urine
  • Poor appetite
  • Altered metabolism
  • Dietary restrictions

Nursing Interventions and Rationales:

  1. Monitor nutritional intake
    Rationale: Ensures adequate nutrition
  2. Provide high-protein meals as ordered
    Rationale: Helps replace protein losses
  3. Monitor serum albumin levels
    Rationale: Indicates nutritional status and treatment effectiveness

Desired Outcomes:

  • The patient will maintain adequate nutritional intake
  • The patient will demonstrate improved albumin levels
  • The patient will maintain a stable weight

Nursing Care Plan 4: Activity Intolerance

Nursing Diagnosis Statement:
Activity Intolerance related to fatigue and fluid retention as evidenced by weakness and decreased ability to perform ADLs.

Related Factors:

  • Generalized weakness
  • Edema
  • Fatigue
  • Altered metabolism

Nursing Interventions and Rationales:

  1. Assess activity tolerance
    Rationale: Determines appropriate activity level
  2. Assist with ADLs as needed
    Rationale: Prevents exhaustion while maintaining function
  3. Encourage progressive activity
    Rationale: Builds strength and endurance

Desired Outcomes:

  • The patient will demonstrate improved activity tolerance.
  • The patient will perform ADLs independently
  • The patient will maintain energy conservation

Nursing Care Plan 5: Knowledge Deficit

Nursing Diagnosis Statement:
Knowledge Deficit related to lack of information about nephrotic syndrome management as evidenced by questions about self-care and verbalized misconceptions.

Related Factors:

  • Complex disease process
  • New diagnosis
  • Multiple medication regimens
  • Lifestyle modifications required

Nursing Interventions and Rationales:

  1. Provide disease education
    Rationale: Increases understanding and compliance
  2. Teach medication management
    Rationale: Ensures proper treatment adherence
  3. Demonstrate self-monitoring techniques
    Rationale: Enables early detection of complications

Desired Outcomes:

  • The patient will verbalize understanding of the disease process
  • The patient will demonstrate proper self-care techniques
  • The patient will identify warning signs requiring medical attention

References

  1. Ackley, B. J., Ladwig, G. B., Makic, M. B., Martinez-Kratz, M. R., & Zanotti, M. (2023). Nursing diagnoses handbook: An evidence-based guide to planning care. St. Louis, MO: Elsevier. 
  2. Harding, M. M., Kwong, J., & Hagler, D. (2022). Lewis’s Medical-Surgical Nursing: Assessment and Management of Clinical Problems, Single Volume. Elsevier.
  3. Herdman, T. H., Kamitsuru, S., & Lopes, C. (2024). NANDA International Nursing Diagnoses – Definitions and Classification, 2024-2026.
  4. Ignatavicius, D. D., Rebar, C., & Heimgartner, N. M. (2023). Medical-Surgical Nursing: Concepts for Clinical Judgment and Collaborative Care. Elsevier.
  5. Nishi S, Ubara Y, Utsunomiya Y, Okada K, Obata Y, Kai H, Kiyomoto H, Goto S, Konta T, Sasatomi Y, Sato Y, Nishino T, Tsuruya K, Furuichi K, Hoshino J, Watanabe Y, Kimura K, Matsuo S. Evidence-based clinical practice guidelines for nephrotic syndrome 2014. Clin Exp Nephrol. 2016 Jun;20(3):342-70. doi: 10.1007/s10157-015-1216-x. PMID: 27099136; PMCID: PMC4891386.
  6. Silvestri, L. A. (2023). Saunders comprehensive review for the NCLEX-RN examination. St. Louis, MO: Elsevier. 
  7. Wendt R, Sobhani A, Diefenhardt P, Trappe M, Völker LA. An Updated Comprehensive Review on Diseases Associated with Nephrotic Syndromes. Biomedicines. 2024 Oct 4;12(10):2259. doi: 10.3390/biomedicines12102259. PMID: 39457572; PMCID: PMC11504437.
  8. Yu X, Han CY. Effect assessment of evidence-based nursing in combination with clinical nursing pathway on nephrotic syndrome care in children: A protocol for systematic review and meta-analysis. Medicine (Baltimore). 2021 Jun 4;100(22):e25990. doi: 10.1097/MD.0000000000025990. PMID: 34087842; PMCID: PMC8183837.
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Anna Curran. RN, BSN, PHN

Anna Curran. RN, BSN, PHN I am a Critical Care ER nurse. I have been in this field for over 30 years. I also began teaching BSN and LVN students and found that by writing additional study guides helped their knowledge base, especially when it was time to take the NCLEX examinations.

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